In an alternate dimension, Peter Parker, Pavitr Prabhakar, and Miguel O'Hara are all Earth's Spider man -- only, Miguel isn't supposed to be in the year 2018 with the others. After a villain attack destroys the city of Nueva York in the year 2099, Miguel O'Hara, also known as Spider-Man 2099, somehow gets thrown decades into the past. It just so happened that Peter B. Parker was the first one to find him in the streets of New York. Grappling with the loss of everyone he loved and with no where else to go, Miguel goes with Peter. Unfortunately for the both of them, new villains are popping up everywhere. So they form a team. Miguel, Peter, Pavitr, and a couple others. New York needs their help, and they'll be there for the city--and for each other.