What happens when Alex Karev takes his five year old daughter with him for his job at the hospital in Seattle. Alex Karev doesn't seem to care very much for anyone but himself. Or at least that's what everyone thought. But when they learn he has a five year old daughter who he's been looking after since the day she was born, they realize just how wrong they were, and Alex is seen in a different light. But raising his daughter as a single father isn't what Alex had thought it would be, and he needs all the help he can get especially when she grow up becoming a young woman?