Jimmy Neutron and the gang are nearly grown up. As they spend the last few months their last year in school together, things start to heat up. and Shane are locked and ready to go on tour for her big chance. Carl is getting ready to head to Peru where he will start his own Llama sanctuary. Jimmy is packing up his lab and heading off to Oxford as soon as graduation is over. Cindy is staying in to help out with the youth theater and is going to the local community college. What happens when Cindy and Jimmy for the last time? Will their fate finally kick in?