In this universe, there is a phenomenon known as the Honkai that occurs periodically throughout history. To exterminate humanity, the Honkai brings about natural disasters and causes widespread epidemics, an example is the Black Death occurred in 1470.
As if the problem was already worse, Honkai creates and spawns its monstrous minions to devour the human race called Honkai Beasts who possess some strong feats from the Honkai.
With these problems painting the whole human race in red blood, they're unable to defy it. It will leave a scar to some people who survive these calamities, however the Honkai's presence will infect the minds of those traumatic survivors at any moment.
For the maidens who possessed the antibodies, the antibodies itself would take on the shapes of unique markings on their skin. Thus, people came to call them Stigmata.
These Stigmata allowed the girls to control the power of the Honkai. Until the Honkai Antibody that had a 1% chance of manifesting appeared on a maiden's body, an individual example is Yae Sakura with the Herrscher of Corruption's manifestation.
In order to fight back against the Honkai, an organization known as Schicksal was founded centuries ago.
After many years of "research", a form of Artificial Antibody that could be injected into the bodies of maidens was created. Schicksal obtained a sample of the Honkai Antibody from the Kaslana and Schariac families. They were identified as Artificial Stigmata.
However due to the lacking samples of Stigmata, the creation of Artificial Stigmata was flawed and a fatal mistake. Not only were they less potent than the Natural Stigmata, they also shortened the wielder's lifespans.
Apart from the Kaslana and Schariac Stigmata, there were also others that existed only in legends. These are classified as True/Legendary Stigmata.
The Legendary Stigmata possess much higher power levels than the Natural type and will stomp the Artificial type like it's nothing. But the bad side is that this symbolizes those people who have been chosen to become a Herrscher: a loyal guard of Honkai to fulfill its goal to destroy humanity.
But one Legendary Stigmata was never obtained by anybody as this was impossible to do and holds a mysterious power. Some tried to obtain it all on their own for personal and greed for power but they died and assimilated in the process.
Dark side of the Moon
Sumeragi (AD Stella 124)
A cryo-pod is now melting as the voice of Yae Sakura is thinking about what happened in the past years of her slumber in the cryo-pod.
Yae Sakura: How long have I been sleeping in that chamber...? I've lost so much my mother, my sister. Now my father and the rest of the clan have been eliminated because of their corrupted doings to us.
As the cryo-pod's cryostasis mode is now disabled, the hatch is opened and ascends the sleeping Sakura in the pod. Two persons are watching her to wake up as her eyes furrow and she groans as her vision is now blurred and slowly becomes clearer as she sees the two people familiar to her.
Yae Sakura: But one thing's for certain, I don't want to see that smile of Kallen's to be gone.
Kallen: Good morning, sweetheart.
Rin: Welcome back to the land of living, my dear sister.
*Opening 2 Season 1 plays*
It's been 2 days since Theresa was rescued from her mission in Nagazora city where she was almost killed by the Stigmata data space that was controlled by RIN. This is her 2nd day of being checked up by a doctor as she's sitting in her hospital bed after being checked up by the doctor named Linda Vashti.

STAI LEGGENDO
Honkai Impact 00 (Gundam Book 2: Simulated Universe story)
FanfictionWhen Y/n was asked by Herta to try the strange VR head set they found, it's simulation maybe more than just any simulated trainings or scenarios he ever had. The control of history in this world is on their hands and their actions. Escape from Nagaz...