In a world where the shows on the Disney Channel are real, the characters are slowly beginning to become self-aware, but every time one becomes aware, the creators dispose of them. When Doctor Doofenshmirtz is suddenly taken off of Phineas and Ferb, Phineas realizes something is not right. With the help of his friends and characters from other shows on the same channel, they slove the case to try and figure out why their friends keep disappearing...all while keeping it hidden from the creators, to ensure they are not the next ones who are disposed of.