A remote African Reservation, a group of teenagers on vacation looking for a good time, Rangers just wanting to protect wildlife, a group of poachers on a job and a Hippopotamus with genetically modified rabies and a taste for human flesh. All the ingredients you need for a horror movie. When a Hippopotamus used to research a way for attack dogs to become more vicious has enough, it escapes from it's captors and into a wildlife Reserve. The company, trying to to save face, hire a group of poachers to kill the animal and recover it's body. However at the same time a group teenagers are on a camping trip trying to get in touch with nature, along with other things, and the Rangers in the reserve are out trying to stop the reoccurring poaching in the area as well train the head Ranger's daughter. But soon they'll find that the problem is bigger than any of them had thought