Do We Have An Adequate Understanding Of The Origin Of The First Life? (Part 2)

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How close are the scientists to understanding the mechanism behind the origins of the very first life?

Scientists are clueless and none understand it, says Dr. James Tour. In fact, he is the one person who has the authority to make such an audacious statement.

Dr. James Tour isn't one of those scientists whose primary occupation is to write books and appear on TV shows. He makes molecules for a living, and he makes it ab initio. He is one of the ten most-cited chemists. He is an active synthetic organic chemist who has more than 130 patents and over 680 research publications. He is the T. T. and W. F. Chao Professor of Chemistry, Professor of Computer Science, Professor of Materials Science and NanoEngineering at Rice University. He was named the World's Most Influential Scientific Minds by Thomson Reuters.1 James Tour claims that scientists are clueless about the origins of the first life:2I have written a long article on the origin of life: http://inference-review.com/article/animadversions-of-a-synthetic-chemist. It is clear, chemists and biologists are clueless. I wrote, "Those who think scientists understand the issues of prebiotic chemistry are wholly misinformed. Nobody understands them. Maybe one day we will. But that day is far from today. It would be far more helpful (and hopeful) to expose students to the massive gaps in our understanding. They may find a firmer—and possibly a radically different—scientific theory. The basis upon which we as scientists are relying is so shaky that we must openly state the situation for what it is: it is a mystery."

He goes on to say that scientists are clueless about the source of the information that's required to build the first cell. In other words, no one knows where that information (to build the very first cell) could have come from. Dr. Tour writes:3

The information or coding within the DNA (or RNA) that corresponds to the sequence of the nucleic acids is primary to the entire discussion of life. Some would rightly argue that the information is even more fundamental than the matter upon which it is encoded. I merely showed that the requisite molecules (lipids, proteins, nucleic acids and carbohydrates) are so unlikely to have occurred in the states and quantities needed, that we could never have gotten to the point of figuring out the genesis of the requisite code or information. The code is analogous to the difference between the Library of Congress and a big box of alphabetic letters— the library has a huge amount of embedded information while the random box of letters has little. So origin of first life is the 'nail holding the coffin closed' on the emergence of biological evolution. Without that first life, or simple cell, which requires the four molecule types plus information, all proposals regarding biological evolution are without the base of life. And it is difficult to discuss biology without life.

But even if one were given all the molecules needed in complete stereochemical purity, and the information code, could a cell be constructed using the chemical and biochemical tools that we have today? I have written about such a hypothetic experiment, and how it would be impossible, using today's expertise, to even construct the lipid bilayer, namely the exterior packaging that holds the cell's nanomachinery in place. Just the lipid bilayer (which itself surrounds thousands of nanosystems) is beyond our ability to synthesize. The conclusion of that thought experiment is that "life based upon amino acids, nucleotides, saccharides and lipids is an anomaly. Life should not exist anywhere in our universe. Life should not even exist on the surface of the earth." "Yet we are led to believe that 3.8 billion years ago the requisite compounds could be found in some cave, or undersea vent, and somehow or other they assembled themselves into the first cell."

J. Warner Wallace of Cold Case Christianity enlightens us more about this dilemma:4The building blocks of life (proteins, ribosomes, enzymes etc.) are formed at the direction of specific nucleotide sequencing in DNA, the largest molecule known. In humans, DNA contains as many as 10 billion atoms. The adenine, guanine, cytosine, and thymine bases in DNA are linked in a particular order to form the genetic code containing the master plan for every organism. The information in DNA guides and instructs the formation of proteins; without it, protein formation would be a haphazard, hit-or-miss proposal. The nucleic sequence in DNA is informational.

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