"That's how it starts, sir. The fever, the rage, the feeling of powerlessness that turns good men... cruel." Ian Isley has dedicated his entire life to helping the criminally insane after losing his father to madness. Against his wife's wishes he moved to Gotham City and applied for a job as a psychiatrist in Arkham Asylum. His caring nature easily allowed him to become attached to the patients in a way no other doctor ever had. So when he uncovers a dark secret that threatens the lives and sanity of every patient in his care, he can't leave well enough alone. The aftermath changes the man for the worst.