This game shows what happens before the events of the first one, where the people that work in the Umbrella Corporation are going in a train to the factory, but they are attacked by animals and creatures, since the T-virus breaks out, and the people get infected and become zombies. Later on, a group of cops from the Umbrella group get to the mansion where the factory and lab is, where the team of cops realize that a scientist that was experimenting with the T-virus, was the one who released it and caused it to spread. Although this scientist has been dead for many years, but has come to life again, due to his experiments. So the special team enters the mansion and have to face some creatures, and later face the dead scientist to win the game.