All Nikki remembers is dying in her bed as her dad desperately tries to save her....but when she wakes up, she is somehow the size of your average thumb, alongside a cat and mouse that also wake up to the same fate, named Isaiah and Mercury. The three shelter themselves in the abandoned house they wake up in, but one early morning, Nikki makes the mistake of attempting to explore the great outdoors alone and gets kidnapped. After escaping, Nikki makes it her mission to return to her friends, but the journey is proven more difficult than easy, given how Nikki is at the feet of many mobians and other creatures that could either be friends or foes. Nevertheless, Nikki will have to face her fears and try to survive in a world of giants at her wake. Not only does she come across friends and foes, but comes across old family as well. Can Nikki survive and get to her friends in time? Or will she be stuck above?