"Tearing it up on Desolation Row, huh? Ha! God, I fuckin' wish." "Fuckin' hate it here, man." "Hey! Why don't you pussies stop your whining and come have some fun?" Gerard, Mikey, Pete, Frank, and Bob are stuck in their shitty hometown, affectionately nicknamed "Desolation Row." Born there, die there. That's how they think it works. Ray and Patrick have great lives on the other side of the city border, where everyone lives in giant houses and eats plenty every night and gets a chance to do whatever they want. They don't think anything could stop them from hating each other. Then a catastrophic problem at the other end of town causes two different lifestyles to clash together.