▼ Kluver Bucy Syndrome ▼

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Klüver-Bucy syndrome (KBS) is an extremely rare brain disorder that can cause memory loss and behavioral problems. Some people with this disease try to eat nonfood items. Others have an unusually extreme sex drive. In severe cases, symptoms include seizures and dementia.

》Klüver-Bucy syndrome is a very rare disease that affects males and females equally.

》Many common symptoms relate to eating or your mouth, like:

Binge eating and purging (bulimia nervosa).

Compulsive eating (hyperphagia), smoking or drinking alcohol.

Eating inedible objects (pica).

Putting objects in your mouth or inappropriate licking (hyperorality).

Other common symptoms include:

Dementia.

Hypersexuality, which is an extreme sex drive marked by inappropriate sexual behavior. (In children, this may present as frequent holding or rubbing of their genitalia or thrusting their pelvis back and forth.)

Inability to recognize familiar people or objects by sight (visual agnosia).

Memory loss (amnesia).

Reduced fear or aggression response (docility).

Seizures.

》You're more likely to develop symptoms of Klüver-Bucy syndrome if you have:

Alzheimer's disease.

Cerebrovascular disease.

Epilepsy.

Head injury or trauma.

Herpes simplex encephalitis.

Pick's disease (frontotemporal dementia).
Stroke.

》The syndrome was first described in 1937 as an experimental neurobehavioral syndrome in monkeys with bitemporal brain lesions; both transient and permanent KBS among among humans have been subsequently observed

》In humans, autoimmune and herpes encephalitis have been reported to cause Klüver-Bucy syndrome in humans. Having all parts of the syndrome is, however, rare — probably because in reality, the syndrome was artificially induced and affected large parts of the brain that might not be normally damaged together.

》There is no cure for Klüver-Bucy syndrome. The disorder is not life-threatening, but the patient can be difficult to manage. With treatment, symptoms may slowly decline.

Treatment is symptomatic and supportive, and may include drug therapy.

Healthcare providers diagnose Klüver-Bucy syndrome using a physical exam and other tests. These may include blood tests and imaging studies such as:

CT scan.

Electroencephalogram (EEG).

MRI.

Early detection is essential for effective treatment. In some cases, Klüver-Bucy syndrome may be mistaken for autism.

Treatment for Klüver-Bucy syndrome depends on your symptoms and underlying condition. It may include:

Antidepressants, mood stabilizers or antipsychotic drugs to manage behavioral issues.

Antiseizure medications to manage seizures.

Antivirals to treat infection.

Carbamazepine or leuprolide to treat sexual behavior problems.

Occupational therapy to help with managing daily activities.

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